Endocrine Abstracts

Introduction: Primary hyperparathyroidism (PHPT) can only be cured by parathyroidectomy (PTX) but mild and asymptomatic cases can often be managed conservatively. We carried out a retrospective audit of patients attending the Endocrine clinic at Watford to determine how our practice compared with the different guidelines for surgical referral published in the USA and the UK.Method: A search was carried out of clinic letters from Jan 2010 to Oct 2011. Add...

A 45-year-old woman presented with a 6-week history of constipation and generalised abdominal pains. Blood biochemistry revealed a corrected serum calcium of 4.99 mmol/l, phosphate 0.82 mmol/l, and intact parathyroid hormone (i-PTH) of 0.2 pmol/l (normal range 1–6.1 pmol/l). Serum parathyroid hormone related peptide (PTH-rP) was 5.3 pmol/l (normal range <1.8 pmol/l). Computed tomography demonstrated an 11.0×11.6 cm ovarian tumour with cystic and solid areas and h...

Background: National Institute for Health and Clinical Excellence (NICE) guidelines advise that GDM be diagnosed using a 2-hr 75 g oral glucose tolerance test (OGTT). However there is lack of consensus on the optimal postpartum surveillance. Current postpartum screening guidance suggests a single fasting plasma glucose (FPG) at 6-weeks with annual testing thereafter. As women with GDM are often from mixed ethnic groups and frequently have postprandial hyperglycaemia, ...

A 50-year-old man with poorly controlled type 2 diabetes mellitus on oral hypoglycaemics was under review as a diabetic outpatient. In April 2007, he developed idiopathic thrombocytopaenic purpura which, on a background of probable diabetic nephropathy, precipitated end-stage renal failure. He was treated with oral steroids and was established on haemodialysis. To achieve better glycaemic control, he was converted to twice daily insulin. His treatment dose of prednisolone was ...